bhaktira - to devotional service; virodhī - averse; karma - activity; dharma - religious; vā - or; adharma - irreligious; tāhāra - of that; kalmaṣa - sin; nāma - the name; sei - this; mahā-tamaḥ - great darkness.

The greatest ignorance consists of activities, whether religious or irreligious, that are opposed to devotional service. They are to be known as sins [kalmaṣa].