yadyapi - although; vṛndāvana-tyāge - to leave Vṛndāvana; nāhi prabhura mana - was not the desire of the Lord; bhakta - of the devotee; icchā - desire; pūrite - to fulfill; kahe - says; madhura vacana - sweet words.

Although Śrī Caitanya Mahāprabhu had no desire to leave Vṛndāvana, He began to speak sweet words just to fulfill the desire of His devotee.