taiche - similarly; eka brahmāṇḍa - one universe; yadi - if; mukta haya - becomes liberated; tabu - still; alpa-hāni - very little loss; kṛṣṇera - of Lord Kṛṣṇa; mane - the mind; nāhi laya - does not take it very seriously.

“In the same way, if one universe is vacated due to the living entities’ having been liberated, that is a very little thing for Kṛṣṇa. He does not take it very seriously.