guṇa-pravāha etasminn
abudhās tv akhilātmanaḥ
gatiḿ sūkṣmām abodhena
saḿsarantīha karmabhiḥ
guna -- of the material modes; pravahe -- in the flow; etasmin -- this; abudhah -- those who are ignorant; tu -- but; akhila -- of everything; atmanah -- of the Soul; gatim -- the destination; sukshmam -- sublime; abodhena -- because of their lack of understanding; samsaranti -- they move through the cycle of birth and death; iha -- in this world; karmabhih -- forced by their material activities.
A soul who forgets his true identity as a servant of God is sent to this world to be imprisoned in a succession of material bodies. Wrongly identifying himself with these bodies, such a conditioned soul suffers the consequent distress of karmic action and reaction. Vasudeva, as a compassionate Vaishnava, laments for the suffering conditioned souls, whose unhappiness, the result of ignorance, can be remedied by knowledge of the principles of devotional service to Lord Krishna.